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ChemicalBook--->CAS DataBase List--->2080306-25-6

2080306-25-6

2080306-25-6 Structure

2080306-25-6 Structure
IdentificationBack Directory
[Name]

Acetamide, N-[[4-[[(2-amino-9H-purin-6-yl)oxy]methyl]phenyl]methyl]-2-[4-[(18-chloro-3,6,9,12-tetraoxaoctadec-1-yl)oxy]-2,3,5,6-tetrafluorophenoxy]-
[CAS]

2080306-25-6
[Synonyms]

Acetamide, N-[[4-[[(2-amino-9H-purin-6-yl)oxy]methyl]phenyl]methyl]-2-[4-[(18-chloro-3,6,9,12-tetraoxaoctadec-1-yl)oxy]-2,3,5,6-tetrafluorophenoxy]-
[Molecular Formula]

C35H43ClF4N6O8
[MOL File]

2080306-25-6.mol
[Molecular Weight]

787.2
Chemical PropertiesBack Directory
[density ]

1.346±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

9.53±0.10(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

HaXS8 is a dimerizer that can promote a covalent and irreversible intracellular dimerization of HaloTag and SNAP-tagged proteins of interest. HaXS8 does not interfere with PI3K/mTOR signaling[1][2].
[storage]

Store at -20°C
[References]

[1] Erhart D, et, al. Chemical development of intracellular protein heterodimerizers. Chem Biol. 2013 Apr 18; 20(4): 549-57. DOI:10.1016/j.chembiol.2013.03.010
[2] Saha I, et, al. Dynamics of the HIV Gag Lattice Detected by Localization Correlation Analysis and Time-Lapse iPALM. Biophys J. 2020 Aug 4; 119(3): 581-592. DOI:10.1016/j.bpj.2020.06.023
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