| Identification | Back Directory | [Name]
TBI-223 | [CAS]
2071265-08-0 | [Synonyms]
TBI-223
methyl (S)-((3-(3-fluoro-4-(2-oxa-6-azaspiro[3.3]heptan-6-yl)phenyl)-2-oxooxazolidin-5-yl)methyl)carbamate
Carbamic acid, N-[[(5S)-3-[3-fluoro-4-(2-oxa-6-azaspiro[3.3]hept-6-yl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-, methyl ester | [Molecular Formula]
C17H20FN3O5 | [MDL Number]
MFCD34475927 | [MOL File]
2071265-08-0.mol | [Molecular Weight]
365.36 |
| Chemical Properties | Back Directory | [Boiling point ]
572.5±50.0 °C(Predicted) | [density ]
1.45±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
11.69±0.46(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
TBI-223 is an orally bioavailable oxazolidinone antibiotic and an antimicrobial. TBI-223 shows activity against Mycobacterium tuberculosis (Mtb)[1][2]. | [IC 50]
Oxazolidinone | [References]
[1] Chauhan A, et al. Comprehensive review on mechanism of action, resistance and evolution of antimycobacterial drugs. Life Sci. 2021;274:119301. DOI:10.1016/j.lfs.2021.119301
[2] Motamen S, et al. Analysis of Approaches to Anti-tuberculosis Compounds. ACS Omega. 2020;5(44):28529-28540. Published 2020 Oct 27. DOI:10.1021/acsomega.0c03177 |
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ChemShuttle, Inc.
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0150-83588313-811 18800520310 |
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www.jiehuapharma.com/ |
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