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ChemicalBook--->CAS DataBase List--->2064175-32-0

2064175-32-0

2064175-32-0 Structure

2064175-32-0 Structure
IdentificationBack Directory
[Name]

(1R)-3-(3,4-dimethoxyphenyl)-1-[2-({[3-(2-{2-[3-(2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}acetamido)propoxy]ethoxy}ethoxy)propyl]carbamoyl}methoxy)phenyl]propyl (2S)-1-[(2S)-2-(3,4,5-trimethoxyphenyl)butanoyl]piperidine-2-carboxylate
[CAS]

2064175-32-0
[Synonyms]

dTAG-7
FKBP12 PROTAC DTAG-7
(1R)-3-(3,4-dimethoxyphenyl)-1-[2-({[3-(2-{2-[3-(2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}acetamido)propoxy]ethoxy}ethoxy)propyl]carbamoyl}methoxy)phenyl]propyl (2S)-1-[(2S)-2-(3,4,5-trimethoxyphenyl)butanoyl]piperidine-2-carboxylate
[Molecular Formula]

C63H79N5O19
[MDL Number]

MFCD31691408
[MOL File]

2064175-32-0.mol
[Molecular Weight]

1210.32
Chemical PropertiesBack Directory
[Melting point ]

78- 83oC
[Boiling point ]

1242.1±65.0 °C(Predicted)
[density ]

1.265±0.06 g/cm3(Predicted)
[storage temp. ]

-20°C Freezer
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

10.68±0.40(Predicted)
[color ]

Off-White to Pale Yellow
Hazard InformationBack Directory
[Uses]

dTAG-7 is a degradation tag which was tested for its efficiency at depleting FKBP12F36V -MELK(sg3R) and was found to have significantly degraded FKBP12F36V -MELK(sg3R) within 4 hours.Used in the study of cancer research.
[IC 50]

FKBP12(F36V); BRD4; Cereblon
[storage]

Store at -20°C
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