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ChemicalBook--->CAS DataBase List--->205654-80-4

205654-80-4

205654-80-4 Structure

205654-80-4 Structure
IdentificationBack Directory
[Name]

Intermediate of Rolapitant
[CAS]

205654-80-4
[Synonyms]

Intermediate of Rolapitant
(2R,4S)-benzyl 5-oxo-2,4-diphenyloxazolidine-3-carboxylate
Benzyl (2r,4s)-5-oxo-2,4-diphenyloxazolidine-3-carboxylate
3-FLUORO-2-NITROPHENOL (2R)-5-OXOPYRROLIDINE-2-CARBOXYLIC ACID
3-Oxazolidinecarboxylic acid,5-oxo-2,4-diphenyl-,phenylmethyl ester,(2R,4S)-
[Molecular Formula]

C23H19NO4
[MDL Number]

MFCD30718663
[MOL File]

205654-80-4.mol
[Molecular Weight]

373.4
Chemical PropertiesBack Directory
[Boiling point ]

591.6±50.0 °C(Predicted)
[density ]

1.270±0.06 g/cm3(Predicted)
[pka]

-3.96±0.60(Predicted)
Hazard InformationBack Directory
[Uses]

(2R,4S)-Benzyl 5-oxo-2,4-diphenyloxazolidine-3-carboxylate is an intermediate in the preparation of Rolapitant (R639800). Rolapitant is an NK1 receptor antagonist that is used in the treatment of chemotherapy-induced nausea and vomiting.
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