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ChemicalBook--->CAS DataBase List--->20424-00-4

20424-00-4

20424-00-4 Structure

20424-00-4 Structure
IdentificationBack Directory
[Name]

Deprodone propionate
[CAS]

20424-00-4
[Synonyms]

Eclar
RD 20000
Desolone
Allomidon
Einecs 243-810-1
deprodone propionate
Deprodone propionate (JAN)
Deprodone propionate (RD20000)
21-Deoxyprednisolone 17-propionate
21-Deoxyprednisolone 17α-propionate
11β,17-Dihydroxypregna-1,4-diene 3,20-dione 17-propionate
3,20-Dioxo-11β-hydroxypregna-1,4-dien-17-ol 17-propionate
11β,17α-Dihydroxy-1,4-pregnadiene-3,20-dione 17-propionate
11beta,17-dihydroxypregna-1,4-diene-3,20-dione 17-propionate
Propionic acid 11β-hydroxy-3,20-dioxo-1,4-pregnadiene-17α-yl ester
Pregna-1,4-diene-3,20-dione, 11-hydroxy-17-(1-oxopropoxy)-, (11β)-
Pregna-1,4-diene-3,20-dione, 11β,17-dihydroxy-, 17-propionate (8CI)
[EINECS(EC#)]

243-810-1
[Molecular Formula]

C24H32O5
[MDL Number]

MFCD00866008
[MOL File]

20424-00-4.mol
[Molecular Weight]

400.508
Chemical PropertiesBack Directory
[Melting point ]

227-229 °C
[Boiling point ]

540.6±50.0 °C(Predicted)
[density ]

1.20±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: 250 mg/mL (624.20 mM)
[form ]

Solid
[pka]

14.09±0.70(Predicted)
[color ]

White to off-white
Raw materials And Preparation ProductsBack Directory
[Raw materials]

p-Toluenesulfonic acid-->Chromium(VI) oxide-->Potassium borohydride-->Hydrocortisone-->Propionic anhydride-->Manganese nitrate-->Prednisone
Hazard InformationBack Directory
[Description]

Deprodone propionate is a new topical antiinflammatory corticosteroid. In animal studies, it exhibited an extremely low skin irritation rate. Another potential use is as an antiasthmatic agent.
[Originator]

Boots (United Kingdom)
[Uses]

Ester of 21-Deoxyprednisolone 17α-Propionate is a topical antiinflammatory agent.
[Definition]

ChEBI: Deprodone propionate is a corticosteroid hormone.
[Brand name]

Eclar
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20423-99-8

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