Identification | Back Directory | [Name]
Cell-permeable Caspase-1 Inhibitor I trifluoroacetate salt | [CAS]
201608-12-0 | [Synonyms]
Cell-permeable Caspase-1 Inhibitor I Cell-permeable Caspase-1 Inhibitor I trifluoroacetate salt Cell-permeable Caspase-1 Inhibitor I trifluoroacetate salt Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Tyr-Val-Ala-Asp-aldehyde (pseudo acid) trifluoroacetate salt | [Molecular Formula]
C97H160N20O24 | [MDL Number]
MFCD01322992 (net) | [MOL File]
201608-12-0.mol | [Molecular Weight]
1990.43 |
Hazard Information | Back Directory | [Uses]
Ac-AAVALLPAVLLALLAP-YVAD-CHO is a cell-permeable caspase-1 inhibitor that has antitumor activity[1]. | [IC 50]
Caspase-1 | [References]
[1] S Schlosser, et al. Inhibition of caspase-1 induces cell death in pancreatic carcinoma cells and potentially modulates expression levels of bcl-2 family proteins. FEBS Lett. 2001 Feb 23;491(1-2):104-8. DOI:10.1016/s0014-5793(01)02144-5 |
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