| Identification | Back Directory | [Name]
1,2-DIMYRISTOYL-3-TRIMETHYLAMMONIUM-PROPANE | [CAS]
197974-74-6 | [Synonyms]
14:0 TAP
TAP (14:0)
1,2-DIMYRISTOYL-3-TRIMETHYLAMMONIUM-PROPANE
N,N,N-Trimethyl-2,3-bis(tetradecanoyloxy)propan-1-aminium chloride | [Molecular Formula]
C34H68NO2+ | [MDL Number]
MFCD00674454 | [MOL File]
197974-74-6.mol | [Molecular Weight]
522.91 |
| Hazard Information | Back Directory | [Description]
TAP (14:0) A cationic lipids that can be used for drug delivery, gene transfection and vaccine delivery. TAP has been proven to be efficient for in vitro and in vivo transfection applications, which makes it one of the most widely used cationic lipids for gene transfection applications. | [Uses]
DMTAP is a cationic lipid that can be used for delivery of DNA, RNAi and drugs[1][2][3]. | [References]
[1] Gurtovenko AA, et al. Cationic DMPC/DMTAP lipid bilayers: molecular dynamics study. Biophys J. 2004 Jun;86(6):3461-72. DOI:10.1529/biophysj.103.038760
[2] Miller AD. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov;10(6):781-811. DOI:10.1586/17434440.2013.855471
[3] Lajunen T, et al. Topical drug delivery to retinal pigment epithelium with microfluidizer produced small liposomes. Eur J Pharm Sci. 2014 Oct 1;62:23-32. DOI:10.1016/j.ejps.2014.04.018 |
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Asymchem Labs.
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Merck KGaA
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Creative Enzymes
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www.creative-enzymes.com |
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