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ChemicalBook--->CAS DataBase List--->1952272-74-0

1952272-74-0

1952272-74-0 Structure

1952272-74-0 Structure
IdentificationBack Directory
[Name]

Bemarituzumab
[CAS]

1952272-74-0
[Synonyms]

Bemarituzumab
Research Grade Bemarituzumab(DHD47901)
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[form ]

Liquid
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Uses]

Bemarituzumab is a first-in-class, humanized IgG1 monoclonal antibody against FGFR2b (a FGF receptor). Bemarituzumab blocks fibroblast growth factors from binding and activating FGFR2b. Bemarituzumab has the potential for cancer research[1].
[References]

[1] Daniel Vt Catenacci, et al. Bemarituzumab with modified FOLFOX6 for advanced FGFR2-positive gastroesophageal cancer: FIGHT Phase III study design. Future Oncol. 2019 Jun;15(18):2073-2082. DOI:10.2217/fon-2019-0141
[2] Xiang H, et al. Preclinical characterization of bemarituzumab, an anti-FGFR2b antibody for the treatment of cancer. MAbs. 2021 Jan-Dec;13(1):1981202.
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