Identification | Back Directory | [Name]
1H-Indole-2-carboxylic acid, 3-[3-(phenylmethoxy)phenyl]- | [CAS]
1888473-12-8 | [Synonyms]
1H-Indole-2-carboxylic acid, 3-[3-(phenylmethoxy)phenyl]- | [Molecular Formula]
C22H17NO3 | [MOL File]
1888473-12-8.mol | [Molecular Weight]
343.38 |
Chemical Properties | Back Directory | [Boiling point ]
578.9±45.0 °C(Predicted) | [density ]
1.298±0.06 g/cm3(Predicted) | [solubility ]
DMSO:34.34(Max Conc. mg/mL);100.0(Max Conc. mM) Ethanol:34.34(Max Conc. mg/mL);100.0(Max Conc. mM) | [pka]
4.36±0.30(Predicted) |
Hazard Information | Back Directory | [Description]
IND 1316 is an activator of AMP-activated protein kinase (AMPK). | [Uses]
IND 1316 is an orally active, blood-brain barrier permeable AMPK activator with neuroprotective effects in animal models of Huntington's disease. IND 1316 can be used for research on neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease[1]. | [storage]
Store at -20°C | [References]
[1] Vela M, et al. Neuroprotective Effect of IND1316, an Indole-Based AMPK Activator, in Animal Models of Huntington Disease. ACS Chem Neurosci. 2022 Jan 19;13(2):275-287. DOI:10.1021/acschemneuro.1c00758 |
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