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ChemicalBook--->CAS DataBase List--->182912-58-9

182912-58-9

182912-58-9 Structure

182912-58-9 Structure
IdentificationBack Directory
[Name]

clenoliximab
[CAS]

182912-58-9
[Synonyms]

Idec 151
clenoliximab
Research Grade Clenoliximab
Immunoglobulin G 4 (human-macaca monoclonal ce9gamma4pe gamma4-chain anti-human antigen cd 4), disulfide with human-macaca monoclonal ce9gamma4pe lambda-chain, dimer
Immunoglobulin G4, anti-(human cd4 (antigen)) (human-macaca-monoclonal ce9gamma4pe gamma4-chain), disulfide with human-macaca monoclonal ce9gamma4pe dambda-chain, dimer
[MDL Number]

MFCD03792953
Chemical PropertiesBack Directory
[Appearance]

Monkey/human chimeric CD4 monoclonal antibodies
Hazard InformationBack Directory
[Chemical Properties]

Monkey/human chimeric CD4 monoclonal antibodies
[Hazard]

A poison.
[Uses]

Clenoliximab (IDEC-151) is a macaque-human chimeric monoclonal antibody (immunoglobulin G4) specific for the CD4 molecule on the surface of T lymphocytes. Clenoliximab can be used for the research of rheumatoid arthritis[1].
[References]

[1] D R Mould, et al. A population pharmacokinetic-pharmacodynamic analysis of single doses of clenoliximab in patients with rheumatoid arthritis. Clin Pharmacol Ther. 1999 Sep;66(3):246-57. DOI:10.1016/S0009-9236(99)70032-9
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