Identification | Back Directory | [Name]
LEM-14 | [CAS]
1814881-70-3 | [Synonyms]
LEM-14 [1]Benzothieno[2,3-d]pyrimidin-4(1H)-one, 2-[[4-[[(3R)-3,4-dihydro-1-oxo-1H-2-benzopyran-3-yl]carbonyl]-1-piperazinyl]methyl]-5,6,7,8-tetrahydro- | [Molecular Formula]
C25H26N4O4S | [MOL File]
1814881-70-3.mol | [Molecular Weight]
478.56 |
Chemical Properties | Back Directory | [Boiling point ]
788.3±70.0 °C(Predicted) | [density ]
1.55±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
3.76±0.10(Predicted) | [color ]
Light brown to gray |
Hazard Information | Back Directory | [Uses]
LEM-14 is a potent NSD2 inhibitor with an IC50 of 132 μM. LEM-14 has the potential for the research of multiple myeloma[1]. | [References]
[1] Shen Y, et al. Identification of LEM-14 inhibitor of the oncoprotein NSD2. Biochem Biophys Res Commun. 2019 Jan 1;508(1):102-108. DOI:10.1016/j.bbrc.2018.11.037 |
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Company Name: |
Wuhan Topule
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Tel: |
+86-02787215551 +86-19945035818 |
Website: |
http://www.topule.com/ |
Company Name: |
cjbscvictory
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Tel: |
13348960310 13348960310 |
Website: |
https://www.weikeqi-biotech.com/ |
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