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ChemicalBook--->CAS DataBase List--->1798871-30-3

1798871-30-3

1798871-30-3 Structure

1798871-30-3 Structure
IdentificationBack Directory
[Name]

Centrinone
[CAS]

1798871-30-3
[Synonyms]

LCR-263
Centrinone
Centrinone (LCR-263)
2-((2-Fluoro-4-((2-fluoro-3-nitrobenzyl)sulfonyl)phenyl)thio)-5-methoxy-N-(5-methyl-1H-pyrazol
2-[[2-Fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(4-morpholinyl)-4-pyrimidinamine
4-Pyrimidinamine, 2-[[2-fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(4-morpholinyl)-
[Molecular Formula]

C26H25F2N7O6S2
[MDL Number]

MFCD28969654
[MOL File]

1798871-30-3.mol
[Molecular Weight]

633.65
Chemical PropertiesBack Directory
[Melting point ]

>187°C (dec.)
[Boiling point ]

924.2±75.0 °C(Predicted)
[density ]

1.59±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C Freezer
[solubility ]

Aqueous Base (Very Slightly), DMSO (Slightly)
[form ]

Solid
[pka]

13.65±0.10(Predicted)
[color ]

Off-White to Pale Brown
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

Centrinone is a reversible inhibitor of Polo-like kinase 4 (Plk4), a serine-threonine protein kinase that initiates centriole assembly.
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

Centrinone(1798871-30-3)1HNMR
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