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Betulinic glycine amide (compound 5a) is a pentacyclic triterpenoid and derivative of Betulinic acid (HY-10529). Betulinic glycine amide has been used as a precursor in the synthesis of betulinic acid derivatives with anticancer and antiviral activity[1]. | [Biological Activity]
Betulinic glycine amide is a pentacyclic triterpenoid and derivative of betulinic acid .1,2 It has been used as a precursor in the synthesis of betulinic acid derivatives with anticancer and antiviral activity. | [References]
1.Soler, F., Poujade, C., Evers, M., et al.Betulinic acid derivatives: A new class of specific inhibitors of human immunodeficiency virus type 1 entryJ. Med. Chem.39(5)1069-1083(1996)
2.Jeong, H.J., Chai, H.B., Park, S.Y., et al.Preparation of amino acid conjugates of betulinic acid with activity against human melanomaBioorg. Med. Chem. Lett.9(8)1201-1204(1999)
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