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ChemicalBook--->CAS DataBase List--->1743-60-8

1743-60-8

1743-60-8 Structure

1743-60-8 Structure
IdentificationBack Directory
[Name]

BETA-ESTRADIOL 17-ACETATE
[CAS]

1743-60-8
[Synonyms]

Estradiol acetate
oestradiol acetate
B-ESTRADIOL 17-ACETATE
β-Estradiol 17-Acetate
Estradiol 17-Monoacetate
BETA-ESTRADIOL 17-ACETATE
(17β)-Estradiol 17-acetate
17-BETA-ESTRADIOL 17-ACETATE
β-Estradiol 17-acetate crude
17β-Acetoxyestra-1,3,5(10)-trien-3-ol
17BETA-ESTRADIOL 17-ACETATE VETRANAL100
1,3,5(10)-estratriene-3,17β-diol 17-acetate
1,3,5(10)-Estratriene-3,17b-diol 17-acetate
1,3,5(10)-ESTRATRIEN-3,17BETA-DIOL 17-ACETATE
1,3,5[10]-ESTRATRIENE-3,17BETA-DIOL 17-ACETATE
(17β)-Estra-1,3,5(10)-triene-3,17-diol 17-Acetate
3,17BETA-DIHYDROXY-1,3,5[10]-ESTRATRIENE 17-ACETATE
Estra-1,3,5(10)-triene-3,17-diol (17β)-, 17-acetate
Acetic acid 3-hydroxyestra-1(10),2,4-triene-17β-yl ester
Acetic acid 3-hydroxyestra-1,3,5(10)-triene-17β-yl ester
1,3,5(10)-Estratriene-3,17β-diol 17-acetate, 3,17β-Dihydroxy-1,3,5(10)-estratriene 17-acetate
β-Estradiol 17-acetate,1,3,5(10)-Estratriene-3,17β-diol 17-acetate, 3,17β-Dihydroxy-1,3,5(10)-estratriene 17-acetate
(8R,9S,13S,14S,17S)-3-hydroxy-13-Methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-yl acetate
[EINECS(EC#)]

605-722-5
[Molecular Formula]

C20H26O3
[MDL Number]

MFCD00056537
[MOL File]

1743-60-8.mol
[Molecular Weight]

314.42
Chemical PropertiesBack Directory
[Melting point ]

210 °C
[Boiling point ]

450.5±45.0 °C(Predicted)
[density ]

1.18±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C Freezer, Under inert atmosphere
[solubility ]

Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly), DMSO (Slightly)
[form ]

neat
[pka]

10.26±0.60(Predicted)
[color ]

White to Off-White
[PH]

6.96 at 24.1℃ and 10g/L
[BRN ]

2625732
[LogP]

4 at 25℃ and pH5
Safety DataBack Directory
[Hazard Codes ]

T
[Risk Statements ]

60-61
[Safety Statements ]

53-45
[WGK Germany ]

3
Hazard InformationBack Directory
[Chemical Properties]

White Solid
[Uses]

Protected Estradiol.
[Definition]

ChEBI: Beta-Estradiol 17-acetate is a steroid ester.
[Brand name]

Femring(Galen); Femtrace (Warner Chilcott).
[Biochem/physiol Actions]

β-Estradiol is a steroid hormone involved in a number of organ functions. It is significantly associated with brain functions including neuroprotection, neurogenesis and synaptic plasticity. β-Estradiol maintains bone homeostasis, and hence is preferred for osteoporosis therapy. 17-β-Estradiol is the most active estrogen generated in our body. During postmenopausal, 17-β-estradiol inhibits oxidative modification in low density lipoprotein. This indicates that estrogen replacement therapy might be useful in treating cardiovascular disease.
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