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ChemicalBook--->CAS DataBase List--->172546-75-7

172546-75-7

172546-75-7 Structure

172546-75-7 Structure
IdentificationBack Directory
[Name]

HIS-CYS-LYS-PHE-TRP-TRP
[CAS]

172546-75-7
[Synonyms]

HCKFWW
HIV INTEGRASE PROTEIN
HIS-CYS-LYS-PHE-TRP-TRP
H-HIS-CYS-LYS-PHE-TRP-TRP-OH
HIV INTEGRASE [IN] INHIBITOR
HIV INTEGRASE PROTEIN INHIBITOR
HIV INTEGRASE PROTEIN INHIBITOR(1)
HIV INTEGRASE PROTEIN INHIBITOR (I)
7:PN:WO2005068492 SEQID:17 unclaimed sequence
L-Tryptophan, L-histidyl-L-cysteinyl-L-lysyl-L-phenylalanyl-L-tryptophyl-
[Molecular Formula]

C46H55N11O7S
[MDL Number]

MFCD00798733
[MOL File]

172546-75-7.mol
[Molecular Weight]

906.06
Chemical PropertiesBack Directory
[Boiling point ]

1395.9±65.0 °C(Predicted)
[density ]

1.367±0.06 g/cm3(Predicted)
[storage temp. ]

−20°C
[form ]

Solid
[pka]

3.38±0.10(Predicted)
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

His-Cys-Lys-Phe-Trp-Trp is an inhibitor for the human immunodeficiency virus (HIV) integrase with an IC50 of 2 μM[1].
[References]

[1] Puras Lutzke RA, et al., Identification of a hexapeptide inhibitor of the human immunodeficiency virus integrase protein by using a combinatorial chemical library. Proc Natl Acad Sci U S A. 1995 Dec 5;92(25):11456-60. DOI:10.1073/pnas.92.25.11456
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