| Identification | Back Directory | [Name]
8-cyclohexyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino[3,2,1-jk]carbazole methanesulfonate | [CAS]
170964-68-8 | [Synonyms]
8-cyclohexyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino[3,2,1-jk]carbazole methanesulfonate | [Molecular Formula]
C21H30N2O3S | [MOL File]
170964-68-8.mol | [Molecular Weight]
390.54 |
| Hazard Information | Back Directory | [Uses]
Tetrindole Mesylate is part of a pharmaceutical composition, which exhibits anti-cancer effects for preventing and treating prostate cancer. | [Definition]
ChEBI:Tetrindole mesylate is a racemate composed of equimolar amounts of (R)- and (S)-tetrindole mesylate. It has a role as an antidepressant, an EC 1.4.3.4 (monoamine oxidase) inhibitor and a serotonergic agonist. It contains a (R)-tetrindole mesylate and a (S)-tetrindole mesylate. | [in vivo]
Tetrindole mesylate (25 mg/kg; po; single dose) inhibits rat brain and liver mitochondrial MAO A by 80% within 0.5-1 hr and the onset of recovery of enzyme activity became evident after 24 hr in male albino rats weighing 180-200 g[1]. | [IC 50]
MAO-A |
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