| Identification | Back Directory | [Name]
25-DESACETYL RIFAMPICIN | [CAS]
16783-99-6 | [Synonyms]
Aids070669
Aids-070669
DeacetylrifaMpin
Desacetylrifampin
DeacetylrifaMpicin
Desacetylrifampicin
25-DesacetylrifaMpin
25-deacetylrifampicin
25-O-DesacetylrifaMpin
25-O-DeacetylrifaMpicin
25-DESACETYL RIFAMPICIN
25-O-Desacetylrifampicin
Rifampicin 25-Desacetyl Impurity
Rifampin Impurity 1(25-Desacetyl Rifampicin)
25-Da-3-(4-methyl-1-piperazinyl-iminomethyl)-rifamycin sv
25-Deacetyl-3-(4-methyl-1-piperazinyl-iminomethyl)-rifamycin sv
25-O-Deacetyl-3-[(E)-[(4-methyl-1-piperazinyl)imino]methyl]rifamycin
Rifamycin, 25-o-deacetyl-3-[(E)-[(4-methyl-1-piperazinyl)imino]methyl]-
Desacetyl RifampicinQ: What is
Desacetyl Rifampicin Q: What is the CAS Number of
Desacetyl Rifampicin Q: What is the storage condition of
Desacetyl Rifampicin Q: What are the applications of
Desacetyl Rifampicin | [Molecular Formula]
C41H56N4O11 | [MDL Number]
MFCD08063717 | [MOL File]
16783-99-6.mol | [Molecular Weight]
780.9 |
| Chemical Properties | Back Directory | [Melting point ]
>300°C | [Boiling point ]
943.1±65.0 °C(Predicted) | [density ]
1.35±0.1 g/cm3(Predicted) | [storage temp. ]
Amber Vial, -20°C Freezer, Under Inert Atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
4.96±0.70(Predicted) | [color ]
Dark Red to Black | [Stability:]
Light Sensitive | [InChIKey]
KUJZTIJOBQNKDR-ACYBWPGYNA-N |
| Hazard Information | Back Directory | [Description]
25-desacetyl rifampicin, also known as 25-deacetyl-rifampicin, is the main metabolite of rifampicin. It has partial activity. Rifampicin mainly treats various forms of tuberculosis. High-Performance Liquid Chromatographic can be used to determine the metabolism of rifampicin in the body by checking the concentration of 25-desacetyl rifampicin in the urine or blood of tuberculosis patients[1-3]. | [Chemical Properties]
Dark Red Solid | [Uses]
A metabolite of Rifampicin. | [storage]
-20°C | [References]
[1]Chik Z, et al. A bioequivalence comparison of two formulations of rifampicin (300- vs 150-mg capsules): An open-label, randomized, two-treatment, two-way crossover study in healthy volunteers.. Clinical Therapeutics, 2011.
[2] Mohan B, et al.Evaluation of the recently reported USP gradient HPLC method for analysis of anti-tuberculosis drugs for its ability to resolve degradation products of rifampicin. Journal of Pharmaceutical and Biomedical Analysis, 2003; 31: 607-612.
[3] Lily, et al. The influence of mutation gene rpoB of Mycobacterium tuberculosis cluster I (507-534) on the elimination 25-desacetyl rifampicin in urine of tuberculosis subjects. IOP Conference Series: Earth and Environmental Science, 2018; 1755-1315.
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