Chemical Properties | Back Directory | [density ]
1.53±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
1.85±0.10(Predicted) | [color ]
Light yellow to green yellow |
Hazard Information | Back Directory | [Description]
GNE-0946 is a potent and selective RORc inverse agonist. | [Uses]
GNE-0946 is a potent and selective RORγ( RORc) agonist with an EC50 value of 4 nM for HEK-293 cell. | [storage]
Store at -20°C | [References]
[1] Fauber BP, et al. Discovery of imidazo[1,5-a]pyridines and -pyrimidines as potent and selective RORc inverse agonists. Bioorg Med Chem Lett. 2015 Aug 1;25(15):2907-12. DOI:10.1016/j.bmcl.2015.05.055 |
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