| Identification | Back Directory | [Name]
SB 220025 | [CAS]
165806-53-1 | [Synonyms]
SB 220025
5-(2-AMINO-4-PYRIMIDINYL)-4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)IMIDAZOLE
5-(2-AMINO-4-PYRIMIDINYL)-4-(4-FLUOROPHENYL)-1-(4-PIPERIDINLYL)IMIDAZOLE
4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl]pyrimidin-2-amine
2-Pyrimidinamine, 4-[4-(4-fluorophenyl)-1-(4-piperidinyl)-1H-imidazol-5-yl]- | [Molecular Formula]
C18H19FN6 | [MDL Number]
MFCD02179213 | [MOL File]
165806-53-1.mol | [Molecular Weight]
338.38 |
| Chemical Properties | Back Directory | [Boiling point ]
611.9±65.0 °C(Predicted) | [density ]
1.42±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
DMSO: 22mg/mL | [form ]
White to pale amber solid. | [pka]
9.92±0.10(Predicted) | [color ]
white to pale yellow |
| Hazard Information | Back Directory | [Definition]
ChEBI: SB220025 is am member of the class of imidazoles carrying piperidin-4-yl, 4-fluophenyl and 2-aminopyrimidin-4-yl substituents at posiitons 1, 4 and 5 respectively. It has a role as an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor, an angiogenesis inhibitor and an anti-inflammatory agent. It is a member of piperidines, an organofluorine compound, an aminopyrimidine and a member of imidazoles. | [Biological Activity]
Primary Target
P38MAPK |
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| Company Name: |
Merck KGaA
|
| Tel: |
(+86) 21 2033 8288 |
| Website: |
http://www.sigmaaldrich.cn |
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