| Identification | Back Directory | [Name]
1,7,13-Trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone, 4,10,16-trimethyl-6,12-bis(1-methylethyl)-18-[(1S)-1-methylpropyl]-3,9,15-tris(phenylmethyl)-, (3S,6R,9S,12R,15S,18R)- | [CAS]
165467-50-5 | [Synonyms]
Beauvericin A
1,7,13-Trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone, 4,10,16-trimethyl-6,12-bis(1-methylethyl)-18-[(1S)-1-methylpropyl]-3,9,15-tris(phenylmethyl)-, (3S,6R,9S,12R,15S,18R)- | [Molecular Formula]
C46H59N3O9 | [MDL Number]
MFCD33021154 | [MOL File]
165467-50-5.mol | [Molecular Weight]
797.98 |
| Chemical Properties | Back Directory | [Boiling point ]
980.7±65.0 °C(Predicted) | [density ]
1.120±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: soluble; Methanol: soluble | [form ]
A solid | [pka]
-1.45±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
Beauvericin A is a cyclodepsipeptide and derivative of beauvericin originally isolated from B. bassiana that has diverse biological activities. It is active against M. tuberculosis (MIC=25 μg/mL) and P. falciparum (IC50=12 μg/mL).2 Beauvericin A is toxic to brine shrimp (LD100=32 μg/mL). | [Biological Activity]
Beauvericin A is a cyclodepsipeptide and derivative of beauvericin originally isolated from B. bassiana that has diverse biological activities.1,2,3 It is active against M. tuberculosis (MIC = 25 μg/ml) and P. falciparum (IC50 = 12 μg/ml).2 Beauvericin A is toxic to brine shrimp (LD100 = 32 μg/ml).3 | [storage]
Store at -20°C | [References]
1.Gupta, S., Montillor, C., and Hwang, Y.-S.Isolation of Novel Beauvericin Analogues from the Fungus Beauveria bassianaJ. Nat. Prod.58(5)733-738(1995)
2.Nilanonta, C., Isaka, M., Kittakoop, P., et al.Antimycobacterial and antiplasmodial cyclodepsipeptides from the insect pathogenic fungus Paecilomyces tenuipes BCC 1614Planta Med.66(8)756-758(2000)
3.Shi, S., Li, Y., Ming, Y., et al.Biological activity and chemical composition of the endophytic fungus Fusarium sp. TP-G1 obtained from the root of Dendrobium officinale Kimura et MigoRec. Nat. Prod.12(6)549-556(2018)
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