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Tabituximab (OTSA101) is a humanized monoclonal antibody against frizzled class receptor 10 (FZD10)[1]. | [in vivo]
Yttrium 90-radiolabeled OTSA101 (OTSA101-DTPA-90Y) shows significant antitumor activity following a single intravenous injection in mouse xenograft model[1]. | [References]
[1] Blagodatski A, et al. Targeting the Wnt pathways for therapies. Mol Cell Ther. 2014 Sep 11;2:28. DOI:10.1186/2052-8426-2-28 |
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