| Identification | Back Directory | [Name]
Olinciguat | [CAS]
1628732-62-6 | [Synonyms]
IW-1701
Olinciguat
Olinciguat (IW-1701)
Propanamide, 3,3,3-trifluoro-2-[[[5-fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(3-isoxazolyl)-1H-pyrazol-3-yl]-4-pyrimidinyl]amino]methyl]-2-hydroxy-, (2R)- | [Molecular Formula]
C21H16F5N7O3 | [MDL Number]
MFCD32174264 | [MOL File]
1628732-62-6.mol | [Molecular Weight]
509.39 |
| Chemical Properties | Back Directory | [Boiling point ]
695.5±55.0 °C(Predicted) | [density ]
1.62±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
9.80±0.29(Predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
Olinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator with concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole cell assay[1]. | [References]
[1] Buys ES, et al. Discovery and development of next generation sGC stimulators with diverse multidimensional pharmacology and broad therapeutic potential. Nitric Oxide. 2018 Aug 1;78:72-80. DOI:10.1016/j.niox.2018.05.009 |
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| Company Name: |
Biorbyt Ltd.
|
| Tel: |
+44 (0)1223 859 353 |
| Website: |
www.biorbyt.com |
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