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ChemicalBook--->CAS DataBase List--->162558-94-3

162558-94-3

162558-94-3 Structure

162558-94-3 Structure
IdentificationBack Directory
[Name]

Broussoflavonol F
[CAS]

162558-94-3
[Synonyms]

Broussoflavonol F
3,5,7-Trihydroxy-2-[4-hydroxy-3-(3-methyl-2-butenyl)phenyl]-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one,3,5,7-trihydroxy-2-[4-hydroxy-3-(3-methyl-2-buten-1-yl)phenyl]-8-(3-methyl-2-buten-1-yl)-
[Molecular Formula]

C25H26O6
[MDL Number]

MFCD29765862
[MOL File]

162558-94-3.mol
[Molecular Weight]

422.47
Chemical PropertiesBack Directory
[Boiling point ]

640.9±55.0 °C(Predicted)
[density ]

1.315±0.06 g/cm3(Predicted)
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

powder
[pka]

6.43±0.40(Predicted)
[color ]

Yellow
Hazard InformationBack Directory
[Description]

Broussoflavonol F has antiplatelet effect, is partially due to an inhibitory effect on cyclooxygenase, can inhibit arachidonic acid (AA)-induced platelet aggregation. Broussoflavonol F shows inhibitory activities on mushroom tyrosinase. 3. Broussoflavonol F shows radical scavenging against 2,2-diphenyl-1-picrylhydrazyl (DPPH), the IC50 value of 708.54 uM. 4. Broussoflavonol F exhibits moderate cytotoxic activities against five human cancer cells with the IC50 value of 0.41-7.2 ug/mL.
[Uses]

Broussoflavonol F possess xanthine oxidase inhibitory activity[1].
[target]

Tyrosinase
[References]

[1] Ryo Miyata, et al. Propolis Components from Stingless Bees Collected on South Sulawesi, Indonesia, and Their Xanthine Oxidase Inhibitory Activity. J Nat Prod. 2019 Feb 22;82(2):205-210. DOI:10.1021/acs.jnatprod.8b00541
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