| Identification | Back Directory | [Name]
camlipixant | [CAS]
1621164-74-6 | [Synonyms]
camlipixant
(S)-Methyl-2-((2-(2,6-difluoro-4-(methylcarbamoyl)phenyl)-7-methylimidazo[1,2-a]pyridin-3-yl)methyl)morpholine-4-carboxylate
4-Morpholinecarboxylic acid, 2-[[2-[2,6-difluoro-4-[(methylamino)carbonyl]phenyl]-7-methylimidazo[1,2-a]pyridin-3-yl]methyl]-, methyl ester, (2S)- | [Molecular Formula]
C23H24F2N4O4 | [MOL File]
1621164-74-6.mol | [Molecular Weight]
458.46 |
| Hazard Information | Back Directory | [Chemical Properties]
Camlipixant is a purinoreceptor antagonist. | [Biological Activity]
Camlipixant (BLU-5937) a potent, selective, non-competitive and orally active P2X3 homotrimeric receptor antagonist with an IC50 of 25 nM against hP2X3 homotrimeric. Camlipixant shows potent anti-tussive effect and no taste alteration. Camlipixant can be used for the research of unexplained, refractory chronic cough.
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