| Identification | Back Directory | [Name]
4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE | [CAS]
162012-70-6 | [Synonyms]
4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE
4-chloro-6-nitro-7-fluoro-quinazoline
Quinazoline, 4-chloro-7-fluoro-6-nitro-
4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE###162012-70-6
Afatinib impurity 6: 4-chloro-7fluoro-6-nitroquinazoline | [EINECS(EC#)]
-0 | [Molecular Formula]
C8H3ClFN3O2 | [MDL Number]
MFCD08063159 | [MOL File]
162012-70-6.mol | [Molecular Weight]
227.58 |
| Chemical Properties | Back Directory | [Boiling point ]
395℃ | [density ]
1.649 | [Fp ]
193℃ | [storage temp. ]
Sealed in dry,Store in freezer, under -20°C | [form ]
solid | [pka]
0.53±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
4-Chloro-7-fluoro-6-nitroquinazoline is an intermediate in the synthesis of Afatinib (A355300), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder. |
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