| Identification | Back Directory | [Name]
BMS-983970 | [CAS]
1584713-87-0 | [Synonyms]
BMS-983970
BMS983970,BMS 983970
Butanediamide, 3-(cyclopropylmethyl)-N1-[(3S)-9-fluoro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-2-(3,3,3-trifluoropropyl)-, (2R,3S)- | [Molecular Formula]
C26H26F4N4O3 | [MDL Number]
MFCD28385842 | [MOL File]
1584713-87-0.mol | [Molecular Weight]
518.5 |
| Chemical Properties | Back Directory | [Boiling point ]
730.2±60.0 °C(Predicted) | [density ]
1.45±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: ≥ 50 mg/mL (96.43 mM); Water: < 0.1 mg/mL (insoluble) | [form ]
Powder | [pka]
10.57±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
BMS-983970 is an oral pan-Notch inhibitor for the treatment of multiplecancers[1]. | [in vivo]
BMS-983970 demonstrates anti-tumor activity in T-cell acute lymphoblastic leukemia (T-ALL) and solid tumor xenograft models[1]. | [References]
[1] Ashvinikumar V. Gavai, et al. Abstract 1643: BMS-983970, an oral pan-Notch inhibitor for the treatment of cancer. Cancer Res October 1, 2014 74; 1643. |
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