天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

ChemicalBook--->CAS DataBase List--->158146-85-1

158146-85-1

158146-85-1 Structure

158146-85-1 Structure
IdentificationBack Directory
[Name]

3-Quinolinecarboxylicacid, 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-(1H-1,2,4-triazol-1-ylmethyl)-,ethyl ester
[CAS]

158146-85-1
[Synonyms]

3-Quinolinecarboxylicacid, 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-(1H-1,2,4-triazol-1-ylmethyl)-,ethyl ester
[Molecular Formula]

C25H26N4O6
[MDL Number]

MFCD00932159
[MOL File]

158146-85-1.mol
[Molecular Weight]

478.5
Chemical PropertiesBack Directory
[Melting point ]

174-175 °C
[Boiling point ]

640.7±65.0 °C(Predicted)
[density ]

1.29±0.1 g/cm3(Predicted)
[pka]

2.53±0.50(Predicted)
Hazard InformationBack Directory
[Uses]

TAK-603 is a potent and orally active antirheumatic agent. TAK-603 inhibits Thl-type cytokine production. TAK-603 has the potential for the research of adjuvant arthritis[1][2].
[in vivo]

TAK-603 (6.25 mg/kg; p.o.; daily) reduces the Thl-type cytokine production both in the arthritic lesion and in the spleen[2].

Animal Model:AA rats[2]
Dosage:6.25 mg/kg
Administration:P.o.; daily
Result:Inhibited arthritic paw swelling with the inhibition rate of 65% and the IFN-y mRNA expression in the arthritic joint was significantly reduced.
[References]

[1] Mizuno M, et al. Syntheses of metabolites of ethyl 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-(1,2,4-triazol-1-ylmethyl)quinoline-3-carboxylate (TAK-603). Tetrahedron, 2006, 62(37), 8707–8714.
[2] Ohta Y, et al. TAK-603 selectively suppresses Th1-type cytokine production and inhibits the progression of adjuvant arthritis. Immunology. 1997 Sep;92(1):75-83. DOI:10.1046/j.1365-2567.1997.d01-2288.x
158146-85-1 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel:
Website: www.targetmol.com/
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website:
Company Name: Suzhou Meishi Biotechnology Co., Ltd.  
Tel: 1173954148q
Website: http://m.approvedhomemanagement.com/ShowSupplierProductsList1822805/0.htm
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
Tags:158146-85-1 Related Product Information

  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.