| Identification | Back Directory | [Name]
VUF 10166 | [CAS]
155584-74-0 | [Synonyms]
VUF 10166
VUF 10166 USP/EP/BP
2-Chloro-3-(4-Methyl-1-piperazinyl)quinoxaline
2-chloro-3-(4-methylpiperazin-1-yl)quinoxaline
Quinoxaline, 2-chloro-3-(4-methyl-1-piperazinyl)- | [Molecular Formula]
C13H15ClN4 | [MDL Number]
MFCD01127814 | [MOL File]
155584-74-0.mol | [Molecular Weight]
262.738 |
| Chemical Properties | Back Directory | [Boiling point ]
389.6±42.0 °C(Predicted) | [density ]
1.279±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
≥26.3 mg/mL in EtOH; insoluble in H2O; ≥38.8 mg/mL in DMSO | [form ]
solid | [pka]
6.55±0.42(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
VUF 10166 is a 5-HT3 receptor antagonist. VUF 10166 exhibits partial agonist activity at 5-HT3A receptors at higher concentrations. VUF 10166 is also histamine H4 receptor antagonist. | [Biological Activity]
vuf10166 is a novel, potent and competitive antagonist for 5-ht3a receptor with ki of 0.04 nm, its affinity at 5-ht3ab receptor is significantly lower. |
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