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ChemicalBook--->CAS DataBase List--->155206-01-2

155206-01-2

155206-01-2 Structure

155206-01-2 Structure
IdentificationBack Directory
[Name]

17- Phenyl Trinor Prostaglandin F2α Methyl Amide
[CAS]

155206-01-2
[Synonyms]

Bimatoprost Impurity 5
Bimatoprost Impurity E
17- Phenyl Trinor Prostaglandin F2α Methyl Amide
17-phenyl trinor Prostaglandin F2.alpha. methyl amide
17- Phenyl Trinor Prostaglandin F2α Methyl Amide (10mg/mL in Ethanol)
(~{Z})-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-methylhept-5-enamide
5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-methyl-, (5Z)-
[Molecular Formula]

C24H35NO4
[MOL File]

155206-01-2.mol
[Molecular Weight]

401.54
Chemical PropertiesBack Directory
[Boiling point ]

621.5±55.0 °C(Predicted)
[density ]

1.159±0.06 g/cm3(Predicted)
[storage temp. ]

-20°C Freezer
[solubility ]

DMSO (Slightly), Ethanol
[form ]

Clear Colourless Solution
[pka]

14.25±0.20(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS02,GHS07
[Signal word ]

Danger
[Hazard statements ]

H225-H319
[Precautionary statements ]

P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
Hazard InformationBack Directory
[Description]

17-phenyl trinor Prostaglandin F (17-phenyl trinor PGF) is a metabolically stable analog of PGF and is a potent agonist for the FP receptor, binding with a relative potency of 756% compared to that of PGF. The ethyl amide of 17-phenyl trinor PGF bimatoprost has been approved for use as an ocular hypotensive drug. 17-phenyl trinor PGF methyl amide is an analog of bimatoprost. Its biological and toxicological properties have not been evaluated.
[Uses]

17-Phenyl Trinor Prostaglandin F2α-Methyl Amide is a stable analog of PGF2α and is a potent agonist of for the FP receptor. Analog of Bimatoprost (B386800), an antiglaucoma agent.
[storage]

Store at -20°C
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