| Identification | Back Directory | [Name]
4-(1H-IMIDAZOL-4-YLMETHYL)-PIPERIDINE | [CAS]
151070-83-6 | [Synonyms]
Immepip
4-(1H-imidazol-5-ylmethyl)piperidine
4-(1H-IMIDAZOL-4-YLMETHYL)-PIPERIDINE
Piperidine, 4-(1H-imidazol-5-ylmethyl)- | [Molecular Formula]
C9H15N3 | [MDL Number]
MFCD00921728 | [MOL File]
151070-83-6.mol | [Molecular Weight]
165.24 |
| Hazard Information | Back Directory | [Uses]
Immepip is a H3 agonist. Immepip can reduce cortical histamine release. Immepip can be used for the research of neurological diseases[1]. | [Definition]
ChEBI: Immepip is a member of piperidines. | [in vivo]
Immepip (i.p.; 5, 10 mg/kg) markedly reduces cortical histamine release, but only weakly promotes sleep in the rat[1]. | Animal Model: | Sprague-Dawley rats[1] | | Dosage: | 5, 10 mg/kg | | Administration: | Intraperitoneally | | Result: | Significantly modulated brain histamine release and slight, albeit significant, decreased in sleep onset latency. |
| [References]
[1] Yves Lamberty, et al. H3 agonist immepip markedly reduces cortical histamine release, but only weakly promotes sleep in the rat. Pharmacol Res. 2003 Aug;48(2):193-8. DOI:10.1016/s1043-6618(03)00094-x |
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