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ChemicalBook--->CAS DataBase List--->151070-83-6

151070-83-6

151070-83-6 Structure

151070-83-6 Structure
IdentificationBack Directory
[Name]

4-(1H-IMIDAZOL-4-YLMETHYL)-PIPERIDINE
[CAS]

151070-83-6
[Synonyms]

Immepip
4-(1H-imidazol-5-ylmethyl)piperidine
4-(1H-IMIDAZOL-4-YLMETHYL)-PIPERIDINE
Piperidine, 4-(1H-imidazol-5-ylmethyl)-
[Molecular Formula]

C9H15N3
[MDL Number]

MFCD00921728
[MOL File]

151070-83-6.mol
[Molecular Weight]

165.24
Chemical PropertiesBack Directory
[Boiling point ]

377.4±22.0 °C(Predicted)
[density ]

1.084±0.06 g/cm3(Predicted)
[pka]

14?+-.0.10(Predicted)
Hazard InformationBack Directory
[Uses]

Immepip is a H3 agonist. Immepip can reduce cortical histamine release. Immepip can be used for the research of neurological diseases[1].
[Definition]

ChEBI: Immepip is a member of piperidines.
[in vivo]

Immepip (i.p.; 5, 10 mg/kg) markedly reduces cortical histamine release, but only weakly promotes sleep in the rat[1].

Animal Model:Sprague-Dawley rats[1]
Dosage:5, 10 mg/kg
Administration:Intraperitoneally
Result:Significantly modulated brain histamine release and slight, albeit significant, decreased in sleep onset latency.
[References]

[1] Yves Lamberty, et al. H3 agonist immepip markedly reduces cortical histamine release, but only weakly promotes sleep in the rat. Pharmacol Res. 2003 Aug;48(2):193-8. DOI:10.1016/s1043-6618(03)00094-x
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