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ChemicalBook--->CAS DataBase List--->150145-89-4

150145-89-4

150145-89-4 Structure

150145-89-4 Structure
IdentificationBack Directory
[Name]

(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE
[CAS]

150145-89-4
[Synonyms]

(S)-MCPG
(+)-MCPG
(alphaS)-alpha-Amino-4-Carbo
(S)-α-Methyl-4-carboxyphenylglycine
(+)-α-methyl-4-carboxyphenylglycine
(S)-ALFA-METHYL-4-CARBOXYPHENYLGLYCINE
(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE
(+)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE
4-((1S)-1-AMINO-1-CARBOXYETHYL)BENZOIC ACID
(S)-alpha-Methyl-4-carboxyphenylglycine(S)-MCPG
S(+)-α-Amino-4-carboxy-α-methyl-benzeneacetic acid
4-[(1S)-1-Ammonio-1-Methyl-2-Oxido-2-Oxoethyl]Benzoate
4-[(1S)-1-Ammonio-2-Keto-1-Methyl-2-Oxido-Ethyl]Benzoate
4-[(1S)-1-Azaniumyl-1-Methyl-2-Oxido-2-Oxo-Ethyl]Benzoate
S(+)-ALPHA-AMINO-4-CARBOXY-ALPHA-METHYL-BENZENEACETIC ACID
(+-)-A-METHYL-4-CARBOXYPHENYLGLYCINE GLU TAMATE RECEPTOR AN
(+)-MCPG, LY367385, S(+)-α-Amino-4-carboxy-α-methyl-benzeneacetic acid
[Molecular Formula]

C10H11NO4
[MDL Number]

MFCD00216858
[MOL File]

150145-89-4.mol
[Molecular Weight]

209.2
Chemical PropertiesBack Directory
[Appearance]

white to off-white solid
[Boiling point ]

425.3±40.0 °C(Predicted)
[density ]

1.390±0.06 g/cm3(Predicted)
[storage temp. ]

Store at RT
[solubility ]

0.1 M NaOH: 15 mg/mL
[form ]

solid
[pka]

1.76±0.10(Predicted)
[color ]

White to off-white
[optical activity]

[α]20/D +89.54°, c = 0.33 in 6 M HCl(lit.)
Hazard InformationBack Directory
[Chemical Properties]

white to off-white solid
[Biological Activity]

Active isomer of (RS)-MCPG ((RS)-a-Methyl-4-carboxyphenylglycine ). Non-selective group I/group II metabotropic glutamate receptor antagonist. Also available as part of the Group I mGlu Receptor Tocriset™ , Group II mGlu Receptor Tocriset™ and Mixed mGlu Receptor Tocriset™ .
[Uses]

Active enantiomer of (±)-MCPG
[Definition]

ChEBI: (S)-alpha-methyl-4-carboxyphenylglycine is a non-proteinogenic alpha-amino acid that is alanine in which the alpha-hydrogen is replaced by a 4-carboxyphenyl group (the S-enantiomer). It is a non-selective group I/group II metabotropic glutamate receptor (mGluR) antagonist. It has a role as a metabotropic glutamate receptor antagonist.
[Biochem/physiol Actions]

(+)-α-Methyl-4-carboxyphenylglycine, also known as MCPG, is a competitive metabotropic glutamate receptor antagonist.
[storage]

Room temperature
Safety DataBack Directory
[Safety Statements ]

24/25
[WGK Germany ]

3
[HS Code ]

29224985
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