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ChemicalBook--->CAS DataBase List--->149732-62-7

149732-62-7

149732-62-7 Structure

149732-62-7 Structure
IdentificationBack Directory
[Name]

fura red
[CAS]

149732-62-7
[Synonyms]

fura red
Fura Red,AM
Fura Red, AM *CAS 149732-62-7*
Fura 2-TH, AM (Known as Fura Red(TM), TM of Molecular Probes)
Glycine, N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-N-[5-[2-[2-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]-2-[(5-oxo-2-thioxo-4-imidazolidinylidene)methyl]-6-benzofuranyl]-, (acetyloxy)methyl ester
[Molecular Formula]

C41H44N4O20S
[MOL File]

149732-62-7.mol
[Molecular Weight]

944.87
Chemical PropertiesBack Directory
[density ]

1.48±0.1 g/cm3(Predicted)
[pka]

6.04±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

Fura Red is a Ca2+-sensitive fluorescent dye, which decreases in fluorescence with rising [Ca2+][1].
[Definition]

ChEBI: A 1-benzofuran substituted at position 2 by a (5-oxo-2-thioxoimidazolidin-4-ylidene)methyl group, and at C-5 and C-6 by heavily substituted oxygen and nitrogen functionalities respectively.
[References]

[1] Floto RA, et al. IgG-induced Ca2+ oscillations in differentiated U937 cells; a study using laser scanning confocal microscopy and co-loaded fluo-3 and fura-red fluorescent probes. Cell Calcium. 1995 Nov;18(5):377-89. DOI:10.1016/0143-4160(95)90053-5
[2] Wendt ER, et al. Ratiometric analysis of fura red by flow cytometry: a technique for monitoring intracellular calcium flux in primary cell subsets. PLoS One. 2015 Apr 2;10(3):e0119532. DOI:10.1371/journal.pone.0119532
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