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ChemicalBook--->CAS DataBase List--->149231-65-2

149231-65-2

149231-65-2 Structure

149231-65-2 Structure
IdentificationBack Directory
[Name]

AC-YVAD-AMC
[CAS]

149231-65-2
[Synonyms]

AC-YVAD-AMC
AC-YVAD-MCA
ACETYL-YVAD-AMC
ICE SUBSTRATE III
Caspase-1 fluoro
AC-YVAD-AMC USP/EP/BP
AC-TYR-VAL-ALA-ASP-AMC
AC-TYR-VAL-ALA-ASP-MCA
CASPASE I SUBSTRATE III
N-Ac-Tyr-Val-Ala-Asp-AMC
N-ACETYL-TYR-VAL-ALA-ASP-AMC
CASPASE-1 FLUOROGENIC SUBSTRATE
CASPASE-1 SUBSTRATE (FLUOROGENIC)
AC-YVAD-AMC ;AC-TYR-VAL-ALA-ASP-AMC
CASPASE-1 SUBSTRATE III, FLUOROGENIC
IL-1B CONVERTING ENZYME SUBSTRATE III
IL-1BETA CONVERTING ENZYME SUBSTRATE III
CASPASE 1 (ICE) SUBSTRATE 2M, FLUOROGENIC
Caspase 1 Substrate 2m (ICE), fluorogenic
AC-TYR-VAL-ALA-ASP-7-AMINO-4-METHYL COUMARIN
IL-1BETA CONVERTING ENZYME (ICE) SUBSTRATE III
ACETYL-TYR-VAL-ALA-ASP-(AMINO-4-METHYLCOUMARIN)
N-ACETYL-TYR-VAL-ALA-ASP 7-AMIDO-4-METHYLCOUMARIN
N-acetyl-tyr-val-ala-asp 7-amido-4-*methylcoumari
N-Acetyl-Tyr-Val-Ala-Asp-7-aMino-4-Methyl couMarin
N-ACETYL-TYR-VAL-ALA-ASP-7-AMINO-4-METHYLCOUMARIN AMC
Caspase 1 Substrate 2m (ICE), fluorogenic: Ac-YVAD-AMC
N-Acetyl-Tyr-Val-Ala-Asp-7-amido-4-methylcoumarin >=99% (TLC), powder
ACETYL-L-TYROSYL-L-VALYL-L-ALANYL-L-ASPARTIC ACID ALPHA-(4-METHYLCOUMARYL-7-AMIDE)
L-α-Asparagine, N-acetyl-L-tyrosyl-L-valyl-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
3-[2-[[2-[[2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]propanoylamino]-4-[(4-methyl-2-oxochromen-7-yl)amino]-4-oxobutanoicaci
3-[2-[[2-[[2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]propanoylamino]-4-[(4-methyl-2-oxochromen-7-yl)amino]-4-oxobutanoic acid
[Molecular Formula]

C33H39N5O10
[MDL Number]

MFCD00171369
[MOL File]

149231-65-2.mol
[Molecular Weight]

665.69
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[solubility ]

DMSO: 10 mM The solution is stable in the dark at −20 °C for more than 1 month if no water is present.
[form ]

powder
[color ]

white
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Ac-YVAD-AMC is an inhibitor for caspase. Ac-YVAD-AMC inhibits bacteria-induced cell death of hypersensitive response (HR) cells[1].
[References]

[1] del Pozo O, et al., Caspases and programmed cell death in the hypersensitive response of plants to pathogens. Curr Biol. 1998 Oct 8;8(20):1129-32. DOI:10.1016/s0960-9822(98)70469-5
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