| Hazard Information | Back Directory | [Description]
NPC 17731 is a bradykinin receptor antagonist. | [Uses]
NPC 17731 is a new bradykinin (BK) receptor antagonist. NPC 17731 antagonized both the contractile and relaxant responses caused by BK in longitudinal smooth muscle with IC50 of 23 and 29 nM, respectively[1]. | [References]
[1] Y S Medeiros, et al. Competitive and selective antagonistic action of NPC 17731 on bradykinin-induced relaxant and contractile responses of the guinea pig isolated ileum. Gen Pharmacol. 1995 Nov;26(7):1507-11. DOI:10.1016/0306-3623(95)00031-3 |
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