| Identification | Back Directory | [Name]
Laflunimus | [CAS]
147076-36-6 | [Synonyms]
Laflunimus
LCBOKWGFIPORJD-QBFSEMIESA-N
2-Propenamide, 2-cyano-3-cyclopropyl-3-hydroxy-N-[3-methyl-4-(trifluoromethyl)phenyl]-, (2Z)- | [Molecular Formula]
C15H13F3N2O2 | [MDL Number]
MFCD28502173 | [MOL File]
147076-36-6.mol | [Molecular Weight]
310.27 |
| Hazard Information | Back Directory | [Uses]
Laflunimus-d4 is labeled Laflunimus (L168510) which is used to treat neuropathic pain and the neuropathic pain syndromes. | [in vivo]
HR325 (50 mg/kg; p.o.; days 14-18 after being injected with SRBC) inhibits the secondary anti-sheep red blood cell (SRBC) antibody response with ID50 values of 38 mg/kg[1]. | Animal Model: | Male CD-1 mice (20-24 g)[1] | | Dosage: | 50 mg/kg | | Administration: | Oral; days 14-18 after being injected with SRBC | | Result: | The level of circulating anti-SRBC IgG in this model was inhibited dose relatedly by orally administered HR325.
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| [storage]
Store at -20°C |
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