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ChemicalBook--->CAS DataBase List--->1467829-71-5

1467829-71-5

1467829-71-5 Structure

1467829-71-5 Structure
IdentificationBack Directory
[Name]

(2S,5R)-2-carbamoyl-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-ylhydrogensulfate
[CAS]

1467829-71-5
[Synonyms]

AZD-2514
EOS-61785
Durlobactam acid
(2S,5R)-2-carbamoyl-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-ylhydrogensulfate
(1R,2S,5R)-2-(Aminocarbonyl)-3-methyl-7-oxo- 1,6-diazabicyclo[3.2.1]oct-3-en-6-yl hydrogen sulfate
Sulfuric acid, mono[(1R,2S,5R)-2-(aminocarbonyl)-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl] ester
[Molecular Formula]

C8H11N3O6S
[MOL File]

1467829-71-5.mol
[Molecular Weight]

277.25
Chemical PropertiesBack Directory
[density ]

1.81±0.1 g/cm3(Predicted)
[pka]

-4.65±0.18(Predicted)
Hazard InformationBack Directory
[Description]

Durlobactam is a beta-lactamase inhibitor used in combination with sulbactam to treat susceptible strains of bacteria in the genus Acinetobacter. It is an analog of avibactam.
[Uses]

Durlobactam can be useful in the study of structural basis of PER-1-mediated cefiderocol resistance and synergistic inhibition of PER-1 by cefiderocol in combination with avibactam or durlobactam in Acinetobacter baumannii.
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