| Identification | Back Directory | [Name]
(7-(5-fluoro-2-methoxyphenyl)-2-((2-isopropoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)thieno[3,2-d]pyrimidin-6-yl)methanol | [CAS]
1462949-64-9 | [Synonyms]
EOS-61938
SAR-348830;SAR 348830
ALK kinase inhibitor-1
SAR348830;SAR-348830;SAR 348830
(7-(5-fluoro-2-methoxyphenyl)-2-((2-isopropoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)thieno[3,2-d]pyrimidin-6-yl)methanol
Thieno[3,2-d]pyrimidine-6-methanol, 7-(5-fluoro-2-methoxyphenyl)-2-[[2-(1-methylethoxy)-4-(4-methyl-1-piperazinyl)phenyl]amino]-
kinase,ALK tyrosine kinase receptor,Anaplastic lymphoma kinase,lymphoma,Anaplastic lymphoma kinase (ALK),inhibit,Inhibitor,Cluster of differentiation 246,ALK kinase inhibitor 1,ALK kinase inhibitor-1,ALK kinase inhibitor1,anaplastic,ALK,CD246 | [EINECS(EC#)]
604-604-1 | [Molecular Formula]
C28H32FN5O3S | [MDL Number]
MFCD29924784 | [MOL File]
1462949-64-9.mol | [Molecular Weight]
537.65 |
| Chemical Properties | Back Directory | [Boiling point ]
735.9±70.0 °C(Predicted) | [density ]
1.300±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 100 mg/mL (185.99 mM; Need ultrasonic) | [form ]
Solid | [pka]
12.88±0.10(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
ALK kinase inhibitor-1 is an anaplastic lymphoma kinase (ALK) inhibitor extracted from patent US20130261106A1 compound I-202[1]. | [References]
[1] Carry JC, et, al. Novel thienopyrimidine derivatives, processes for the preparation thereof and therapeutic uses thereof. US20130261106A1. |
|
|