| Identification | Back Directory | [Name]
FG-4592 interMediate | [CAS]
1455091-10-7 | [Synonyms]
ROXA-030
FG-4592 INT
FG4592 intermediates
Roxadustat Impurity 4
FG-4592 interMediate
Roxadustat Impurity 13
Roxadustat Impurity 25
4-Hydroxy-7-phenoxy-3-isoquinolinecarboxylic
methyl 4-hydroxy-7-phenoxyisoquinoline-3-carboxylate
4-hydroxy-7-phenoxyisoquinoline-3-carboxylic acid methyl ester
4-Hydroxy-7-phenoxy-3-isoquinolinecarboxylic acid methyl ester
3-Isoquinolinecarboxylic acid, 4-hydroxy-7-phenoxy-, methyl ester | [Molecular Formula]
C18H15NO4 | [MDL Number]
MFCD29075436 | [MOL File]
1455091-10-7.mol | [Molecular Weight]
298.77 |
| Chemical Properties | Back Directory | [Boiling point ]
534.7±45.0 °C(Predicted) | [density ]
1.320±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [pka]
5.80±0.50(Predicted) | [InChI]
InChI=1S/C17H13NO4/c1-21-17(20)15-16(19)14-8-7-13(9-11(14)10-18-15)22-12-5-3-2-4-6-12/h2-10,19H,1H3 | [InChIKey]
YTWDBRIDKWWANA-UHFFFAOYSA-N | [SMILES]
C1C2=C(C=CC(OC3=CC=CC=C3)=C2)C(O)=C(C(OC)=O)N=1 |
| Hazard Information | Back Directory | [Uses]
Methyl 4-Hydroxy-7-phenoxyisoquinoline-3-carboxylate is an intermediate of N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine (H948180), a hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor used to increase white blood cell levels in blood and hematopoietic progenitor cells in bone marrow. |
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