天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

ChemicalBook--->CAS DataBase List--->1454920-20-7

1454920-20-7

1454920-20-7 Structure

1454920-20-7 Structure
IdentificationBack Directory
[Name]

4-(4-(5,5-diMethyl-4,5-dihydrothiazol-2-yl)piperazin-1-yl)-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyriMidine
[CAS]

1454920-20-7
[Synonyms]

4-(4-(5,5-Dimethyl-4,5-dihydrothiazol-2-yl)piperazin-1-yl)-6-(2,2,2-trifluoroethyl)thieno[2,3-
4-(4-(5,5-diMethyl-4,5-dihydrothiazol-2-yl)piperazin-1-yl)-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyriMidin
4-(4-(5,5-diMethyl-4,5-dihydrothiazol-2-yl)piperazin-1-yl)-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyriMidine
Thieno[2,3-d]pyrimidine, 4-[4-(4,5-dihydro-5,5-dimethyl-2-thiazolyl)-1-piperazinyl]-6-(2,2,2-trifluoroethyl)-
[Molecular Formula]

C17H20F3N5S2
[MDL Number]

MFCD29044864
[MOL File]

1454920-20-7.mol
[Molecular Weight]

415.5
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

MI-2-2 is a menin inhibitor. MI-2-2 binds to menin with low nanomolar affinity and very effectively disrupts the bivalent protein-protein interaction between menin and mixed lineage leukemia (MLL).
[Uses]

MI-2-2 is a potent menin-MLL inhibitor. MI-2-2 binds to menin with low nanomolar affinity (Kd=22nM) and very effectively disrupts the bivalent protein-protein interaction between menin and MLL. MI-2-2 has specific and very pronounced activity in MLL leukemia cells, including inhibition of cell proliferation, down-regulation of Hoxa9 expression, and differentiation[1].
[References]

[1] Shi A, et al. Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia. Blood. 2012;120(23):4461-4469. DOI:10.1182/blood-2012-05-429274
1454920-20-7 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website: www.targetmol.com/
Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel: 86-571-88216897,88216896 13588875226 , 13588875226
Website: www.hzclap.com/en
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525 , +8618327326525
Website: topule.com/
Company Name: Chengdu Feibo Pharm Technology Co., Ltd  
Tel: +86 028-84641798 15982321820
Website: www.arkpharm.com
Company Name: Yancheng Orgunion Pharmaceutical Sci & Tech Co., Ltd.  
Tel: 0515-89701588 13770166955
Website: http://www.orgunion.com
Company Name: Sichuan Wei Keqi Biological Technology Co., Ltd.  
Tel: 028-81700200 18116577057
Website: https://www.weikeqi-biotech.com/
Company Name: Shanghai Lollane Biological Technology Co.,Ltd.  
Tel: 021-52996696,15000506266 15000506266
Website: http://www.bioll.com
Company Name: Yancheng KangdiSen Pharmaceutical Co., Ltd.  
Tel: 13812573443
Website: http://m.approvedhomemanagement.com/ShowSupplierProductsList19142/0.htm
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Tel: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: Shanghai QianYan Bio-technology Co., Ltd  
Tel: 02781293128
Website: m.approvedhomemanagement.com/ShowSupplierProductsList19348/0.htm
Company Name: Chuzhou KeMail Chemical Technology Co., Ltd  
Tel: 0550-5196001 15000891977
Website: http://m.approvedhomemanagement.com/ShowSupplierProductsList19947/0.htm
Company Name: Wuxi KaideRui Pharmaceutical Technology Co., Ltd  
Tel: 19906241957
Website: http://m.approvedhomemanagement.com/ShowSupplierProductsList20128/0.htm
Company Name: Hangzhou Molcore Biopharmatech Co.,Ltd  
Tel: 400-711-5280 86-571-81025280
Website: www.molcore.com
Company Name: Aishilun biotechnology (Shanghai) co., LTD  
Tel: 021-50676523 18019098996
Website: www.acelybio.com
Company Name: Wuxi Donghe Pharmaceutical Technology Co., Ltd.  
Tel: 63313187 15358055255
Website: http://www.cegchemical.com
Company Name: Shanghai Yihua Chemical Co., Ltd.  
Tel: 021-6785342
Website: m.approvedhomemanagement.com/ShowSupplierProductsList621525/0.htm
Company Name: Zhengzhou convergence chemical co., LTD  
Tel: 0371-0371-55153829 18003835034
Website: http://m.approvedhomemanagement.com/supplier/24021783/
Company Name: Hubei Kele Fine Chemical Co., Ltd  
Tel: 027-59101668 19945030958
Website: http://www.kerle.cn
Tags:1454920-20-7 Related Product Information

  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.