| Hazard Information | Back Directory | [Uses]
Lilotomab (HH1) is a murine anti-CD37 monoclonal antibody. Lilotomab reduces clonogenic survival. Lilotomab shows anti-tumor activity[1]. | [in vivo]
Lilotomab (0.5 mg/kg; i.v.; once) inhibits tumor growth in mice[1]. | Animal Model: | SCID mice (DOHH2 cell xenografts)[1] | | Dosage: | 0.5?mg/kg | | Administration: | I.v.; once | | Result: | Inhibited tumor growth and increased mouse survival. |
| [References]
[1] Malenge MM, et al. 177Lu-Lilotomab Satetraxetan Has the Potential to Counteract Resistance to Rituximab in Non-Hodgkin Lymphoma. J Nucl Med. 2020 Oct;61(10):1468-1475. DOI:10.2967/jnumed.119.237230 |
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