| Identification | Back Directory | [Name]
4-(4-FLUOROBENZOYL)-1-(4-PHENYLBUTYL)PIPERIDINE OXALATE | [CAS]
144734-36-1 | [Synonyms]
4F 4PP OXALATE
4-(4-FLUOROBENZOYL)-1-(4-PHENYLBUTYL)PIPERIDINE OXALATE
(4-Fluorophenyl)(1-(4-phenylbutyl)piperidin-4-yl)methanone oxalate
selective,potentials,Inhibitor,Serotonin Receptor,4F 4PP,ketanserin,5-HT Receptor,inhibit,4F 4PP oxalate,5-HT2C,5-hydroxytryptamine Receptor,DAMGO | [Molecular Formula]
C24H28FNO5 | [MDL Number]
MFCD00673877 | [MOL File]
144734-36-1.mol | [Molecular Weight]
429.48 |
| Hazard Information | Back Directory | [Uses]
4F 4PP oxalate is a selective SR-2A antagonist. | [Biological Activity]
A selective 5-HT 2A antagonist with almost as high affinity (K i = 5.3 nM) as ketanserin but with a much lower affinity for 5-HT 2C sites (K i = 620 nM). | [in vivo]
4F 4PP (100 nM) reduces the lowest [D-ala2,N-me-phe4,gly.l5]-enkephalin (DAMGO) concentration and can produce a significant depression of evoked field potentials[1]. | [IC 50]
5-HT2A Receptor: 5.3 nM (Ki); 5-HT2C Receptor: 620 nM (Ki) | [storage]
Store at RT |
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