| Identification | Back Directory | [Name]
ML67-33 | [CAS]
1443290-89-8 | [Synonyms]
ML67-33
ML67 33,ML6733,ML-67-33
Acridine, 2,7-dichloro-9,10-dihydro-9,9-dimethyl-10-[2-(2H-tetrazol-5-yl)ethyl]- | [Molecular Formula]
C18H17Cl2N5 | [MDL Number]
MFCD32215313 | [MOL File]
1443290-89-8.mol | [Molecular Weight]
374.27 |
| Chemical Properties | Back Directory | [Boiling point ]
586.8±60.0 °C(Predicted) | [density ]
1.357±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
4.79±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
ML67-33 is a selective activator of temperature- and mechano-sensitive K2P channels. ML67-33 rapidly and reversibly affects K2P2.1 (TREK-1) with EC50s of 36.3 μM and 9.7 μM in cell-free and HEK293 cells, respectively[1]. | [storage]
Store at -20°C | [References]
[1] Bagriantsev SN, et al. A high-throughput functional screen identifies small molecule regulators of temperature- and mechano-sensitive K2P channels. ACS Chem Biol. 2013 Aug 16;8(8):1841-51. DOI:10.1021/cb400289x |
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| Company Name: |
cjbscvictory
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| Tel: |
13348960310 13348960310 |
| Website: |
https://www.weikeqi-biotech.com/ |
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