| Identification | Back Directory | [Name]
JAK2-IN-4 | [CAS]
1438284-00-4 | [Synonyms]
JAK2-IN-4
JAK2-IN-4 (COMPOUND 16H)
JAK-2-IN-4,JAK2 IN 4,JAK2IN4
2-Pyrimidinamine, 5-methyl-N-[4-(4-morpholinyl)phenyl]-4-[4,5,6,7-tetrahydro-5-(methylsulfonyl)furo[3,2-c]pyridin-2-yl]- | [Molecular Formula]
C23H27N5O4S | [MDL Number]
MFCD30747859 | [MOL File]
1438284-00-4.mol | [Molecular Weight]
469.56 |
| Hazard Information | Back Directory | [Description]
JAK2-IN-4 (compound 16h) is a selective JAK2/JAK3 inhibitor, with IC50 values of 0.7 nM and 23.2 nM for JAK2 and JAK3, respectively[1].
IC50: 0.7 nM/23.2 nM (JAK2/JAK3)[1]. | [Uses]
JAK2-IN-4 (compound 16h) is a selective JAK2/JAK3 inhibitor, with IC50 values of 0.7 nM and 23.2 nM for JAK2 and JAK3, respectively[1]. | [storage]
Store at -20°C | [References]
[1]. Wang Y, et al. Identification of 4-(2-furanyl)pyrimidin-2-amines as Janus kinase 2 inhibitors. Bioorg Med Chem. 2017 Jan 1;25(1):75-83. |
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