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ChemicalBook--->CAS DataBase List--->1433857-09-0

1433857-09-0

1433857-09-0 Structure

1433857-09-0 Structure
IdentificationBack Directory
[Name]

Lascufloxacin hydrochloride
[CAS]

1433857-09-0
[Synonyms]

KRP-AM1977Y
Lascufloxacin HCl
Lascufloxacin hydrochloride
[Molecular Formula]

C21H25ClF3N3O4
[MOL File]

1433857-09-0.mol
[Molecular Weight]

475.89
Hazard InformationBack Directory
[Uses]

Lascufloxacin (KRP-AM1977) hydrochloride is a potent antibacterial compound candidate with broad-spectrum activity against various clinical isolates. Lascufloxacin hydrochloride shows the most potent activity against Gram-positive bacteria compared to other tested quinolones. Lascufloxacin hydrochloride demonstrates incomplete cross-resistance against existing quinolone-resistant strains. Lascufloxacin hydrochloride has potent inhibitory activity against both wild-type and mutated target enzymes.
[Biological Activity]

Lascufloxacin hydrochloride has potent activity against a broad range of pathogens, including aerobic and anaerobic strains, and is able to inhibit both wild-type and mutant targets, making it effective against fluoroquinolone-resistant bacterial strains.
[Synthesis]

The synthesis of Lascufloxacin hydrochloride can follow the route below
Lascufloxacin hydrochloride
Lascufloxacin hydrochloride
[References]

[1] In Vitro Activities and Spectrum of the Novel Fluoroquinolone Lascufloxacin (KRP-AM1977) DOI:10.1128/AAC.00120-17
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