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ChemicalBook--->CAS DataBase List--->1429651-50-2

1429651-50-2

1429651-50-2 Structure

1429651-50-2 Structure
IdentificationBack Directory
[Name]

HPOB
[CAS]

1429651-50-2
[Synonyms]

HPOB
CS-1829
N-hydroxy-4-(2-((2-hydroxyethyl)(phenyl)amino)-2-oxoethyl)benzamide
4-[(Hydroxyamino)carbonyl]-N-(2-hydroxyethyl)-N-phenyl-benzeneacetamide
Benzeneacetamide, 4-[(hydroxyamino)carbonyl]-N-(2-hydroxyethyl)-N-phenyl-
4-[(hydroxyamino)carbonyl]-N-(2-hydroxyethyl)-N-phenyl- benzeneacetamide HPOB
[Molecular Formula]

C17H18N2O4
[MDL Number]

MFCD27952937
[MOL File]

1429651-50-2.mol
[Molecular Weight]

314.34
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

DMSO: soluble1mg/mL, clear (warmed)
[form ]

powder
[color ]

white to beige
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

HPOB is a histone deacetylase 6 inhibitor used in the enhancement of anti-cancer drugs.
[Biological Activity]

HPOB is a very potentselective inhibitor of HDAC6. HPOB inhibits proliferation of normal and transformed cell lines but does not induce cell death. The compound HPOB potentiates the effects of DNA-damaging cytotoxic anti-cancer drugs.
Spectrum DetailBack Directory
[Spectrum Detail]

HPOB(1429651-50-2)1HNMR
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