| Identification | Back Directory | [Name]
KIN1148 | [CAS]
1428729-56-9 | [Synonyms]
KIN1148
KIN1148;KIN-1148;KIN 1148
N-(Benzo[1,2-d:3,4-d']bis(thiazole)-2-yl)-2-naphthamide
N-Benzo[1,2-d:3,4-d']bisthiazol-2-yl-2-naphthalenecarboxamide
2-Naphthalenecarboxamide, N-benzo[1,2-d:3,4-d']bisthiazol-2-yl- | [Molecular Formula]
C19H11N3OS2 | [MDL Number]
MFCD28371902 | [MOL File]
1428729-56-9.mol | [Molecular Weight]
361.44 |
| Chemical Properties | Back Directory | [density ]
1.531±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:55.25(Max Conc. mg/mL);152.86(Max Conc. mM) | [form ]
Solid | [pka]
9.80±0.43(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
N-Benzo[1,2-d:3,4-d'']bisthiazol-2-yl-2-naphthalenecarboxamide, can be used in the synthesis of other chemical compounds having therapeutic activity, such anti-viral compounds. | [in vivo]
Prime-boost immunization of mice with a suboptimal dose of a monovalent pandemic influenza split virus H1N1 A/California/07/2009 vaccine plus KIN1148 protect against a lethal challenge with mouse-adapted influenza virus (A/California/04/2009) and induce an influenza virusspecific IL-10 and Th2 response by T cells derived from lung and lung-draining lymph nodes. Primeboost immunization with vaccine plus KIN1148, but not prime immunization alone, induce antibodies capable of inhibiting influenza virus hemagglutinin and neutralizing viral infectivity. Nevertheless, a single immunization with vaccine plus KIN1148 provide increased protection over vaccine alone and reduce viral load in the lungs after challenge[1]. |
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| Company Name: |
Cool Pharm, Ltd
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| Tel: |
021-58581007 18019463053 |
| Website: |
http://www.coolpharm.com |
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