| Identification | Back Directory | [Name]
3'-DT CEP | [CAS]
142103-12-6 | [Synonyms]
3'-DT CEP
5-METHYL-3'-DU CEP
5-Me-3'-dU-2'-phosphoramidite
3'-Deoxy-5'-O-DMT-5-methyluridine 2'-CE phosphoramidite
5’-O-(4,4-Dimethoxytrityl)-3’-deoxy-5-methyl uridine-2’-CED-phosphoramidite
5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-3'-deoxy-5-methyluridine 2'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-deoxy-5-methyl-, 2'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] | [Molecular Formula]
C40H49N4O8P | [MDL Number]
MFCD08062012 | [MOL File]
142103-12-6.mol | [Molecular Weight]
744.81 |
| Hazard Information | Back Directory | [Uses]
5-Me-3’-dU-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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