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ChemicalBook--->CAS DataBase List--->1402837-79-9

1402837-79-9

1402837-79-9 Structure

1402837-79-9 Structure
IdentificationBack Directory
[Name]

IDO-IN-5
[CAS]

1402837-79-9
[Synonyms]

IDO-IN-5
NLG-1489
IDO IN 5,IDOIN5
5H-Imidazo[5,1-a]isoindole-5-ethanol, 6-fluoro-α-(trans-4-hydroxycyclohexyl)-, (αR,5R)-
[Molecular Formula]

C18H21FN2O2
[MDL Number]

MFCD29472255
[MOL File]

1402837-79-9.mol
[Molecular Weight]

316.38
Chemical PropertiesBack Directory
[Boiling point ]

555.4±35.0 °C(Predicted)
[density ]

1.42±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

14.66±0.20(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

IDO-IN-5 (NLG-1489) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, compound 1489, has an IC50 of 1-10 μM.

IDO-IN-5 (Compound 1487) is an indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 1-10 μM (this is the concentration of IDO-IN-5 at which inhibits 50% of enzymatic activity using recombinant human IDO)[1].

[Uses]

IDO-IN-5 (NLG-1489) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, compound 1489, has an IC50 of 1-10 μM.
[IC 50]

IDO: 1-10 μM (IC50)
[References]

[1]. Mario Mautino, et al. Fused imidazole derivatives useful as ido inhibitors. WO 2012142237 A1.

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