1397695-86-1

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1397695-86-1 Structure

Identification	Back Directory
[Name] DMG-PEG(2000)
[CAS] 1397695-86-1
[Synonyms] DMG-MPEG DMG-PEG2k（GMP）
[Molecular Formula] (C2H4O)nC32H62O5
[MOL File] 1397695-86-1.mol

Safety Data	Back Directory
[Symbol(GHS) ] GHS07
[Signal word ] Warning
[Hazard statements ] H315-H319
[Precautionary statements ] P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Hazard Information	Back Directory
[Uses] DMG-PEG is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles[1].
[References] [1] Nie T, et al. Surface Coating Approach to Overcome Mucosal Entrapment of DNA Nanoparticles for Oral Gene Delivery of Glucagon-like Peptide 1. ACS Appl Mater Interfaces. 2019 Aug 21;11(33):29593-29603. DOI:10.1021/acsami.9b10294

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