| Identification | Back Directory | [Name]
2-(2-BOC-AMINOETHOXY)ETHANOL | [CAS]
139115-91-6 | [Synonyms]
125303
Boc-NH-PEG2
139115-91-6
BocNH-PEG2-OH
CAS_139115-91-6
PROTAC Linker 11
N-Boc-PEG2-alcohol
t-boc-N-amido-PEG2-alcohol
BOC-2-(2-AMINOETHOXY)ETHANOL
2-(2-BOC-AMINOETHOXY)ETHANOL
2-[2-(Boc-amino)ethoxy]ethanol 97%
N-Boc-2-(2-hydroxyethoxy)ethylamine
N-Boc-2-(2-hydroxyethoxy)ethanamine
2-(2-tert-Butoxycarbonylaminoethoxy)ethanol
2-(2-tert-butyloxycarbonylaminoethoxy)ethanol
tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbaMate
tert-butyl N-[2-(2-hydroxyethoxy)ethyl]carbamate
[2-(2-Hydroxyethoxy)ethyl]carbamic Acid tert-Butyl Ester
N-[2-(2-Hydroxyethoxy)ethyl]carbamic acid tert-butyl ester
[2-(2-Hydroxyethoxy)ethyl]carbamic acid 1,1-dimethylethyl ester
Carbamic acid, N-[2-(2-hydroxyethoxy)ethyl]-, 1,1-dimethylethyl ester
Carbamic acid, [2-(2-hydroxyethoxy)ethyl]-, 1,1-dimethylethyl ester (9CI) | [Molecular Formula]
C9H19NO4 | [MDL Number]
MFCD04038542 | [MOL File]
139115-91-6.mol | [Molecular Weight]
205.25 |
| Chemical Properties | Back Directory | [Boiling point ]
332.9±22.0 °C(Predicted) | [density ]
1.061 g/mL at 25 °C | [refractive index ]
n20/D1.454 | [Fp ]
>110℃ | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) | [form ]
clear liquid | [pka]
12.20±0.46(Predicted) | [color ]
Colorless to Light orange to Yellow |
| Hazard Information | Back Directory | [Description]
N-Boc-PEG2-alcohol is a PEG linker containing a hydroxyl group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The Boc group can be deprotected under mild acidic conditions to form the free amine. | [Uses]
2-[2-(Boc-amino)ethoxy]ethanol is N-terminal protected 2-(2-aminoethoxy)ethanol. It is generally used as a molecular spacer/linker. Some of such applications are:
- Synthesis of biotinylated HaloLigands to prepare quantum dot adducts for HaloTag protein-mediated specific labeling of live cells.
- It is one of the key precursors for the total synthesis of tyroscherin and photo-activatable tyroscherin-based affinity reagent used for identification of tyroscherin binding proteins.
- It can be used to link HaloTag enzyme with fluorescent zinc indicator, ZIMIR to monitor the dynamics of regulated secretion of zinc in real time.
- It can also be used to synthesize amphiphiles for DNA and siRNA delivery.
| [IC 50]
PEGs; Alkyl/ether |
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